At the Ohio State University, Scientists have developed a new Nanochip that is considered to be a major breakthrough in human cell regeneration, since it could lead a medical revolution in how we treat injuries and organ regeneration.
This can all be achieved researchers say with a single touch of a small device, the size of a penny, that could help regrow organs and limbs and repair damaged tissues.
It seems like science fiction but then as a CIA Agent interviewed in a TV Documentary mention once, that what is science ‘fiction’ today is always, but always science fact tomorrow.
Very true and nowhere is that statement more relevant than the emerging field of Nano-technologies.
In this article we look at a ingenious new tiny device that sits on the skin and uses an electrical force field to reprogram cells.
It is a penny-sized pad that scientists have developed which enables the ability to regenerate damaged organs and limbs and the healing of horrific wounds.
Tissue Nanotransfection (TNT)
Its a novel concept that could herald a breakthrough in healing the injured and even change the ageing process. The new innovative medical technique is called Tissue NanoTransfection or TNT and is based on using Nanochips, that are placed on the surface of the skin of a living patient.
A small and focused electric field is applied that fires DNA into the skin cells that will cause the cells to convert into a family of natural cells. These cells are ‘tricked’ by containing a set of instructions to help repair the damaged areas in need of healing, such as arteries and even complex organs like the heart.
It offers the possibility of turning the patient’s own tissues into a ‘bio-reactor’ that engineer cells to restore nearby tissues. Alternatively, they can be taken and used on another part of the person’s body for healing and repair.
Basically, the researchers are able to turn skin cells into any type of cell that the body requires to heal itself.
It is really like a new skin patch that is placed on a wounded area. Studies show it can even regrow damaged organs and regenerate injured limbs based on the clinical experiments that have been done on animals.
The device itself is shaped as a square black chip and is no bigger than a penny or finger nail. It operates by adding a droplet of genetic code and then firing it with a source of energy (electrical current). This process takes no more than a second and the Nanochip does not have to stay with you.
This means that once the procedure has been done the Nanochip is removed as the set of instructions has been downloaded and now the regeneration process within the cells starts to take place.
One of the scientists on this research at Ohio State University is Dr. Chandan Sen. He pointed out that by using their new Nanochip technology, it means that patients with injured or compromised organs can be replaced.
Dr Sen is the director of the Center for Regenerative Medicine and Cell-Based Therapies that operates at the Ohio States’ Wexner Medical Center. He was one of those leading this project.
Sen highlights that their research shows that skin is a fertile ground where you can grow the elements of any organ that is declining.
This new amazing research was peer reviewed and published in the Science Journal of Nature Nanotechnology and reveals how the team developed both the new technique and the novel genes. Allowing them to reprogram skin cells on the surface of the animal subjects.
Initial trials done showed that the Nano-technology could help damaged blood vessels be fully restored to complete function within days.
The video presentation below reports of this Breakthrough Device that Heals Organs with a single touch.
Limb Salvaging on Mice and Pigs
The study and research reveals that its effects can be seen within days of first use. While clinical trials have not yet been conducted on humans yet, the potential of the regeneration of any human cells are endless.
In one procedure they saw blood flow to a severely wounded leg of a mouse being regenerated within a week since the Nano-pad reprogrammed skin cells to create new vascular cells.
This is very significant as the femoral artery is a limb’s major blood supply. This main artery was severed but then with this process it was healing and restored.
You see, one of the challenges in saving a limb of a patient is make sure the blood supply takes hold when carrying out major surgery on the arm or leg that was severed or badly damaged.
Researchers put the chip on the animal’s damaged limb, delivered the required genetic code and witnessed blood vessels grown and tissues regenerate of the legs within 7 to 14 days.
‘We preprogrammed their skin cells to become vascular cells… Within a week we began noticing the transformation.’
On the second week, they noticed that active blood vessels had formed and into the third week the legs of the mice where saved and no other form of treatment was required.
Normally with such injuries this would be devastating, resulting in amputation at the damaged site as the only course of treatment.
However, in this case the mice were able to run again.
This shows that powerful and new limb salvaging techniques can be developed that would give the surgeon, trained with this technology, better and more flexible options when trying to save and repair a limb or organ.
The team also duplicated the tests in pigs with astonishing results, with a 98 percent rate of success. This leg-healing process was done after the Walter Reed National Military Medical Center in Bethesda, Maryland had expressed an interest in this research.
Additional experiments on the brain of mice where also done, showing powerful results. The chip was placed on to the leg with different a genetic code or proteins and the neurological cells grew in this area.
A few weeks later the scientists detected the firing of neurons. These new developed cells where then taken from the leg and inserted into the animal’s brain for healing tumors.
This has the potential to develop new innovative treatments for Brain Tumors, Alzheimer and Parkinson diseases.
This TNT project was conducted with a team of 26 researchers that started small with the aim of regenerating the damaged limbs in mice over a 14 day period. Eventually the Military got interested at Walter Reed mentioned above and the research evolved into a much grander scale where they duplicated this leg healing on pigs.
They concluded that this technology can help troops on the battle field whom are injured but it would need to be applied to the patient within 72 hours of the injury occurring, if it is to be successful treatment.
It is no surprise that the military were interested in this kind of research with the potential to heal the limbs in mice and pigs as they have been doing extensive research into figuring out how to regrow limbs with stem cell research.
Along with and new kinds of limb salvaging techniques. I discuss about this at great length in a previous article on AFIRM (or The Arm Forces Institute of Regenerative Medicine).
Also in a more recent article I discussed what the U.S. Military have being doing with limb regeneration research where scientists are studying in helping to reverse engineer what the Axolotl Salamander does in regrowing lost limbs.
The Twenty-Six researchers come from a variety of backgrounds in the fields of science, medicine and engineering where they all worked together to develop and improve on this Nano-technology that is no bigger than a finger nail.
You can read a detail synopsis of this compelling research about their Nanochip technology for restoring tissues and regenerating organs.
Lets look at Related Research
This is a number of dot connecting that can be observed here with the regeneration research done at the Ohio State University.
To begin, one of the phenomena that they were applying was an electric current to instruct the cells for regeneration and healing. The use of Bioelectricity is something that the Scientist Dr. Robert O. Becker did extensive research, but his findings were largely ignored by the scientific profession.
It looks like he was well ahead of his time and more of his work is gaining more recognition. You can read about his material in the highly recommend book, Electric Body.
In addition, I also wrote the following detailed article on the connections with Limb Regeneration and Bioelectricity.
I would say there is a connection with Bioelectricity and Nanotechnology and hopefully more extensive research will be explored deeper into this for regeneration.
Sometime ago I posted research of Golden Nanoparticles that scientists in Tel Aviv University, Israel where working on.
This was a new development in tissue engineering and regenerative medicine involving the process of inserting gold particles of Nano-probes into cardiac tissues. The purpose of this was to improve the electric signals and communications in cells.
Golden Nanoparticles have a special property of super conductivity power which could hold the potential of overcoming the challenges with signaling in regeneration.
If you are a scientist reading this or are connected in some way with the team at Ohio State University above, perhaps you can forward this information to them in case the research done on Gold Nanoparticles in Israel is of value.
The Future Is Now
Dr. Chandan Sen is aiming to get approval from the FDA (Food and Drug Administration) so they can conduct human clinical trials with this Nanochip technology. Its possible they may get approval for next year. This will allow them to show human feasibility.
Following on from this the flood gates can open with the technology being widely used in five years.
However, they did say it may take some time before it becomes readily available and you can read their comments here.
There is no laboratory based procedures ahead of its use so this means that patients could just pick it up from a GP surgery when it becomes available.
The scientists point out this technology is non-evasive and works almost like a syringe, but the chip is the vaccination device and what you place on the device (set of DNA/RNA instructions) is like what would be contained inside the vaccination.
I think it is worth finishing off with a few words of how radical and huge this technology is. This kind of technology is only the beginning and you will see new developments in the near future.
For example, the company that is involved creating the Nanochip is already producing them locally and the technology has gained interest from a Taiwan based Foxconn Technology Group.
You would be forgiven if you were thinking this technology sounds very Star Trek like. In fact the scientific concept was even predicted in Star Trek and now it is a reality.
It can be rather uncanny but if you look at the Borg in Star Trek where they used Nano technology to assimilate their subjects into the hive mind collective. Nano technology was also used with the Borg to regenerate.
You can almost see how the above Nano-technology that is just starting in its infancy of what can start to resemble what the Borg were doing.
Such technology in the real world would be devastating in the wrong hands but then that has always been the case with the abuse of technologies. Nuclear power can be a great and wonderful thing as an energy source but in the wrong hands but can be appalling.
It is not the science knowledge but the abuse of it and the wrong intent.
I believe with the right kind of checks and balances in place we will be fine and will not lose our humanity as some claim but will enhance it. Expanding on Humanity’s Soul and Creative Accomplishments.
Another thought worth looking at is are we more advance that we think we are?
I am certain if you look at all these scientific disciplines and research, they have probably figured out regeneration and even limb regeneration. If they all came together as One then phenomenal discoveries could be realized with a group focused effort.
This may sound a bit of a stretch but you may have heard about the advancements of Robots and how they are becoming very life like. You cannot not tell the difference from a distance if it is a human or not.
In fact a group of scientists in Oxford University in the Britain, claim that the scientific knowledge to develop robots with human flesh on the outside similar to the Terminator movies, already exists.
If we are that well advanced then Human Limb Regeneration, Breast Regeneration, Organ Regeneration and even Immortality, should be a walk in the park?
However, since we don’t communicate and different groups work in their own separate area of medical expertise, then developments keep isolated.
I love to know your thoughts of what has been discussed in this article, feel free to comment below.